Kim Publishes Manuscript in Journal of Experimental Biology

Former Demas lab undergraduate student Kim Long’s manuscript on the effects of acute immune activation on kisspeptin-induced reproductive hormone release was recently published in the Journal of Experimental Biology! Kim conducted this research for her undergraduate honors thesis and was mentored by former Demas lab graduate students Alison Bailey and Tim Greives. In this study, Kim showed that a single treatment of lipopolysaccharide (LPS) is sufficient to block kisspeptin-induced increases in circulating testosterone levels, but does not affect circulating luteinizing hormone levels. Together, Kim’s findings suggest that acute LPS exposure rapidly reduces gonadal sensitivity to HPG stimulation which, in turn, inhibits gonadal steroid release.

A link to the manuscript can be found under the “Publications” page and can also be accessed here.

Image credit: Wahab et al. 2018 (Frontiers in Endocrinology)

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

Powered by WordPress.com.

Up ↑

%d bloggers like this: